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Suri S, Schmidt CE. Photopatterned collagen-hyaluronic acid interpenetrating polymer network hydrogels. Acta Biomater. Microbial hyaluronic acid production. Appl Microbiol Biotechnol. Yamada T, Kawasaki T. Microbial synthesis of hyaluronan and chitin: new approaches. J Biosci Bioeng.

Genetically modified organism - Wikipedia

Production methods for hyaluronan. Int J Carbohydr Chem. Microbial production of hyaluronic acid: current state, challenges, and perspectives. Microb Cell Fact. Chong BF, Blank L. Metabolic engineering of hyaluronic acid production.


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DeAngelis PL. Molecular directionality of polysaccharide polymerization by the Pasteurella multocida hyaluronan synthase. Purification and lipid dependence of the recombinant hyaluronan synthases from Streptococcus pyogenes and Streptococcus equisimilis. Metabolic control of hyaluronan synthases. Matrix Biol. Loss of srfencoded nucleotide sugar transporter activity in Caenorhabditis elegans alters surface antigenicity and prevents bacterial adherence.

Determination of nucleotides and sugar nucleotides involved in protein glycosylation by high-performance anion-exchange chromatography: sugar nucleotide contents in cultured insect cells and mammalian cells. Anal Biochem. Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: differential effects on glucosamine 6-phosphate, UDP- N -acetylglucosamine, and ATP levels.

Kumari K, Weigel PH. Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from Group C Streptococcus equisimilis.

Genetically modified organism

Jagannath S, Ramachandran KB. Influence of competing metabolic processes on the molecular weight of hyaluronic acid synthesized by Streptococcus zooepidemicus. Biochem Eng J. UDP-glucose pyrophosphorylase: up-regulation in hypertrophic cartilage and role in hyaluronan synthesis.

Biochem J. An engineered hyaluronan synthase: characterization for recombinant human hyaluronan synthase 2 Escherichia coli. Growth and amino acid requirements of hyaluronic-acid-producing Streptococcus zooepidemicus. Weigel PH. Functional characteristics and catalytic mechanisms of the bacterial hyaluronan synthases. Enzymological characterization of recombinant xenopus DG42, A vertebrate hyaluronan synthase. Metabolic engineering of Pichia pastoris for production of hyaluronic acid with high molecular weight.

J Biotechnol. Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. Carbohydrates, lipids, and other natural products: three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. Hyaluronan synthase of chlorella virus PBCV CPS1, a homolog of the Streptococcus pneumoniae type 3 polysaccharide synthase gene, is important for the pathobiology of Cryptococcus neoformans.

Infect Immun. Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infection. Eukaryot Cell. Gibson JF, Johnston S. Immunity to Cryptococcus neoformans and C. Fungal Genet Biol. Prolonged synthesis of hyaluronan by Chlorella cells infected with chloroviruses.

Hyaluronan synthesis in virus PBCVinfected chlorella-like green algae. Magyar T, Lax A. Bacteria: Pasteurella multocida. Encycl Food Saf. The capsule biosynthetic locus of Pasteurella multocida A Insight into hyaluronic acid molecular weight control. Identification and molecular cloning of a unique hyaluronan synthase from Pasteurella multocida. Mao Z, Chen RR.

Recombinant synthesis of hyaluronan by Agrobacterium sp. Biotechnol Prog. A recombinant E. Carbohydrates, lipids, and other natural products: molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis molecular cloning, expression, and characterization of the authentic. Identification and disruption of two discrete loci encoding hyaluronic acid capsule biosynthesis genes hasA , hasB , and hasC in Streptococcus uberis.

Evolution of the hyaluronic acid synthesis has operon in Streptococcus zooepidemicus and other pathogenic Streptococci.

References

J Mol Evol. Fermentation process development for hyaluronic acid production by Streptococcus zooepidemicus ATCC Korean J Chem Eng. Isolation of a Streptococcus pyogenes gene locus that directs hyaluronan biosynthesis in acapsular mutants and in heterologous bacteria. Dougherty B, van de Rijn I.

Molecular characterization of hasA from an operon required for hyaluronic acid synthesis in group A Streptococci. Crater DL, Rijn I. Hyaluronic acid synthesis operon has expression in group A Streptococci. Selection of a Streptococcus equi mutant and optimization of culture conditions for the production of high molecular weight hyaluronic acid. Enzyme Microb Technol. Hyaluronan molecular weight is controlled by UDP- N -acetylglucosamine concentration in Streptococcus zooepidemicus.

Hyaluronic acid production by Streptococcus zooepidemicus in marine by-products media from mussel processing wastewaters and tuna peptone viscera. Effect of oxygen and shear stress on molecular weight of hyaluronic acid. J Microbiol Biotechnol. Hyaluronic acid production is enhanced by the additional co-expression of UDP-glucose pyrophosphorylase in Lactococcus lactis. Hyaluronic acid production by recombinant Lactococcus lactis.

Transcription analysis of hyaluronan biosynthesis genes in Streptococcus zooepidemicus and metabolically engineered Lactococcus lactis. Enhanced hyaluronic acid production in Bacillus subtilis by coexpressing bacterial hemoglobin. Use of induction promoters to regulate hyaluronan synthase and UDP-glucosedehydrogenase of Streptococcus zooepidemicus expression in Lactococcus lactis : a case study of the regulation mechanism of hyaluronic acid polymer. J Appl Microbiol.

Tools for genetic manipulations in Corynebacterium glutamicum and their applications. An evolving hierarchical family classification for glycosyltransferases. J Mol Biol. Engineering the E. Yu H, Stephanopoulos G. Metabolic engineering of Escherichia coli for biosynthesis of hyaluronic acid. Metab Eng.

Appl Environ Microbiol. Hyaluronic acid production in Bacillus subtilis. Metabolic engineering of Bacillus subtilis for the efficient biosynthesis of uniform hyaluronic acid with controlled molecular weights. Bioresour Technol.

Yeast-derived recombinant DG42 protein of Xenopus can synthesize hyaluronan in vitro. Production of human hyaluronidase in a plant-derived protein expression system: plant-based transient production of active human hyaluronidase. Protein Expr Purif. Hyaluronan synthesis in cultured tobacco cells BY-2 expressing a chlorovirus enzyme: cytological studies. Biotechnol Bioeng. Chromosomal integration of hyaluronic acid synthesis has genes enhances the molecular weight of hyaluronan produced in Lactococcus lactis.

Biotechnol J. Enterococcus faecalis : its role in root canal treatment failure and current concepts in retreatment.